產品名稱：26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3) Antibody

PSMD3 Antibody is a Rabbit Polyclonal against PSMD3. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.

Target	26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	ELISA: 1/40000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthesized peptide derived from the Internal region of human PSMD3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43242 (UniProt, ExPASy)
UniProt Secondary AC	B3KMW9, B4DT72, Q96EI2, Q9BQA4
UniProt Entry Name	PSMD3_HUMAN
Gene Symbol	PSMD3
GeneID	5709
OMIM	617676
NCBI Accession	NP_002800.2 NM_002809.3
HGNC	9560
KEGG	hsa:5709
Ensembl	ENSG00000108344
String	9606.ENSP00000264639
Buffer	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3)