產品名稱：26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5) Antibody

PSMD5 Antibody is a Rabbit Polyclonal against PSMD5. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

Target	26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	proteasome(prosome, macropain) 26S subunit, non-ATPase, 5
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q16401 (UniProt, ExPASy)
UniProt Secondary AC	B4DZM8, Q15045, Q4VXG8
UniProt Entry Name	PSMD5_HUMAN
Gene Symbol	PSMD5
GeneID	5711
OMIM	604452
NCBI Accession	NP_001257356.1 NM_001270427.1 NP_005038.1 NM_005047.3
HGNC	9563
KEGG	hsa:5711
Ensembl	ENSG00000095261
String	9606.ENSP00000210313
Molecular Weight	Observed MW: 50 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5)