產品名稱：26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13) Antibody

26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13) Antibody is a Rabbit Polyclonal against 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.

Target	26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q9UNM6 (UniProt, ExPASy)
UniProt Secondary AC	B3KT15, O75831, Q53XU2, Q9UNV3
UniProt Entry Name	PSD13_HUMAN
Gene Symbol	PSMD13
GeneID	5719
OMIM	603481
NCBI Accession	NP_002808.3 NM_002817.3 NP_787128.2 NM_175932.2
HGNC	9558
Ensembl	ENSG00000185627
Molecular Weight	Observed MW: 45 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13)