產品詳情
簡單介紹:
5-Hydroxytryptamine Receptor 3A (HTR3A) Antibody
詳情介紹:
HTR3A Antibody is a Rabbit Polyclonal antibody against HTR3A. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Research Articles on 5-Hydroxytryptamine Receptor 3A (HTR3A)
Target | 5-Hydroxytryptamine Receptor 3A (HTR3A) |
Clonality | Polyclonal |
Reactivity | Human, Mouse, Rat |
Tested Applications | WB, IHC |
Host | Rabbit |
Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24-241 of human HTR3A. |
Isotype | IgG |
Form | Liquid |
Purification | Purified by affinity chromatography. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P46098 (UniProt, ExPASy) |
UniProt Secondary AC | B4DSY6, G5E986, O60854, Q7KZM7, Q99918, Q9BSZ9 |
UniProt Entry Name | 5HT3A_HUMAN |
Gene Symbol | HTR3A |
GeneID | 3359 |
NCBI Accession | NP_000860.2 |
KEGG | hsa:3359 |
String | 9606.ENSP00000347754 |
Molecular Weight | Calculated MW: 55 kDa Observed MW: 55 kDa |
Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
Concentration | 0.55 mg/ml |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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