產品名稱：5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1) Antibody

PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosesynthetic pathways.

Target	5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (AMPK alpha)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 474-502 amino acids from human AMPK alpha (PRKAA1).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13131 (UniProt, ExPASy)
UniProt Secondary AC	A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4
UniProt Entry Name	AAPK1_HUMAN
KEGG	hsa:5562
String	9606.ENSP00000346148
Molecular Weight	Calculated MW: 64 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (AMPK alpha)