產品詳情
簡單介紹：
AKT3 (pS472) Antibody
詳情介紹：
AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
Research Articles on AKT3 (pS472)
| Target | AKT3 (pS472) |
| Clonality | Polyclonal |
| Target Modification | Ser472 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S472 of human AKT3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y243 (UniProt, ExPASy) |
| UniProt Secondary AC | Q0VAA6, Q5VTI1, Q5VTI2, Q96QV3, Q9UFP5 |
| UniProt Entry Name | AKT3_HUMAN |
| NCBI Accession | NP_001193658.1 NP_005456.1 NP_859029.1 |
| String | 9606.ENSP00000263826 |
| Enzyme Commission Number | EC 2.7.11.1 EC 2.7.11 |
| Molecular Weight | Calculated MW: 55.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat AKT3. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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