產品詳情
簡單介紹：
Alpha-1-Antitrypsin (AAT) Antibody
詳情介紹：
AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
Research Articles on Alpha-1-Antitrypsin (AAT)
| Target | Alpha-1-Antitrypsin (AAT) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human AAT expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01009 (UniProt, ExPASy) |
| UniProt Entry Name | A1AT_HUMAN |
| GeneID | 5265 |
| KEGG | hsa:5265 |
| String | 9606.ENSP00000416066 |
| Molecular Weight | 47 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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