產品詳情
簡單介紹：
Aldose Reductase (AKR1B1) Antibody
詳情介紹：
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
Research Articles on Aldose Reductase (AKR1B1)
| Target | Aldose Reductase (AKR1B1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 290-316 amino acids from the C-terminal region of human AKR1B1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15121 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R8N3, Q5U031, Q6FGA4, Q6ICP2, Q9BS21, Q9UCI9 |
| UniProt Entry Name | ALDR_HUMAN |
| Gene Symbol | AKR1B1 |
| GeneID | 231 |
| OMIM | 103880 |
| NCBI Accession | NP_001619.1 |
| HGNC | 381 |
| KEGG | hsa:231 |
| Ensembl | ENSG00000085662 |
| String | 9606.ENSP00000285930 |
| Enzyme Commission Number | EC 1.1.1.21 |
| Molecular Weight | Calculated MW: 35.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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