Anti-67kDa Laminin Receptor antibody (196-295) [S0MR] (STJ11103600) STJ11103600|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-67kDa Laminin Receptor antibody (196-295) [S0MR] (STJ11103600)
產品型號：STJ11103600
產品廠商：ST john's laboratory
產品文檔：

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簡單介紹：

Anti-67kDa Laminin Receptor antibody (196-295) [S0MR] (STJ11103600)

詳情介紹：

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-67kDa Laminin Receptor (196-295) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S0MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	RPSA
Gene ID:	3921
Uniprot ID:	RSSA_HUMAN
Immunogen Region:	196-295
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 196-295 of human Laminin Receptor (P08865).
Immunogen Sequence:	EVMPDLYFYRDPEEIEKEEQ AAAEKAVTKEEFQGEWTAPA PEFTATQPEVADWSEGVQVP SVPIQQFPTEDWSAQPATED WSAAPTAQATEWVGATTDWS

Post Translational Modifications	Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association. Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
Function	Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9. (Microbial infection) Acts as a receptor for the Dengue virus. (Microbial infection) Acts as a receptor for the Sindbis virus. (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus. (Microbial infection) Acts as a receptor for the pathogenic prion protein. (Microbial infection) Acts as a receptor for bacteria.
Protein Name	Small Ribosomal Subunit Protein Us2 37 Kda Laminin Receptor Precursor 37lrp 37/67 Kda Laminin Receptor Lrp/Lr 40s Ribosomal Protein Sa 67 Kda Laminin Receptor 67lr Colon Carcinoma Laminin-Binding Protein Laminin Receptor 1 Lamr Laminin-Binding Protein Precursor P40 Lbp/P40 Multidrug Resistance-Associated Protein Mgr1-Ag Nem/1chd4
Database Links	Reactome: R-HSA-156827 Reactome: R-HSA-156902 Reactome: R-HSA-1799339 Reactome: R-HSA-192823 Reactome: R-HSA-2408557 Reactome: R-HSA-6791226 Reactome: R-HSA-72649 Reactome: R-HSA-72689 Reactome: R-HSA-72695 Reactome: R-HSA-72702 Reactome: R-HSA-72706 Reactome: R-HSA-72764 Reactome: R-HSA-9010553 Reactome: R-HSA-9633012 Reactome: R-HSA-9735869 Reactome: R-HSA-9754678 Reactome: R-HSA-975956 Reactome: R-HSA-975957
Cellular Localisation	Cell Membrane Cytoplasm Nucleus 67lr Is Found At The Surface Of The Plasma Membrane With Its C-Terminal Laminin-Binding Domain Accessible To Extracellular Ligands 37lrp Is Found At The Cell Surface In The Cytoplasm And In The Nucleus Colocalizes With Ppp1r16b In The Cell Membrane
Alternative Antibody Names	Anti-Small Ribosomal Subunit Protein Us2 antibody Anti-37 Kda Laminin Receptor Precursor antibody Anti-37lrp antibody Anti-37/67 Kda Laminin Receptor antibody Anti-Lrp/Lr antibody Anti-40s Ribosomal Protein Sa antibody Anti-67 Kda Laminin Receptor antibody Anti-67lr antibody Anti-Colon Carcinoma Laminin-Binding Protein antibody Anti-Laminin Receptor 1 antibody Anti-Lamr antibody Anti-Laminin-Binding Protein Precursor P40 antibody Anti-Lbp/P40 antibody Anti-Multidrug Resistance-Associated Protein Mgr1-Ag antibody Anti-Nem/1chd4 antibody Anti-RPSA antibody Anti-LAMBR antibody Anti-LAMR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-67kDa Laminin Receptor antibody (196-295) [S0MR] (STJ11103600)