產品詳情
簡單介紹：
Anti-A-RAF antibody (166-290) [S8MR] (STJ11103628)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-A-RAF (166-290) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S8MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IHC-P 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARAF |
| Gene ID: | 369 |
| Uniprot ID: | ARAF_HUMAN |
| Immunogen Region: | 166-290 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 166-290 of human A-RAF (P10398). |
| Immunogen Sequence: | RQHEAPSNRPLNELLTPQGP SPRTQHCDPEHFPFPAPANA PLQRIRSTSTPNVHMVSTTA PMDSNLIQLTGQSFSTDAAG SRGGSDGTPRGSPSPASVSS GRKSPHSKSPAEQRERKSLA DDKKK |
| Tissue Specificity | Predominantly in urogenital tissues. |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2. Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation. |
| Protein Name | Serine/Threonine-Protein Kinase A-Raf Proto-Oncogene A-Raf Proto-Oncogene A-Raf-1 Proto-Oncogene Pks |
| Database Links | Reactome: R-HSA-5673000 Reactome: R-HSA-5674135 Reactome: R-HSA-5675221 Reactome: R-HSA-6802946 Reactome: R-HSA-6802948 Reactome: R-HSA-6802952 Reactome: R-HSA-6802955 Reactome: R-HSA-9649948 Reactome: R-HSA-9656223 Reactome: R-HSA-9726840 Reactome: R-HSA-9726842 |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase A-Raf antibody Anti-Proto-Oncogene A-Raf antibody Anti-Proto-Oncogene A-Raf-1 antibody Anti-Proto-Oncogene Pks antibody Anti-ARAF antibody Anti-ARAF1 antibody Anti-PKS antibody Anti-PKS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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