5HT2C Receptor Blocking Peptide peptide (STJ505510) STJ505510-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：5HT2C Receptor Blocking Peptide peptide (STJ505510)
產品型號：STJ505510-250
產品廠商：ST john's laboratory
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5HT2C Receptor Blocking Peptide peptide (STJ505510)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	5HT2C Receptor Blocking Peptide is synthetically produced from the 400-458 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	HTR2C
Gene ID:	3358
Uniprot ID:	5HT2C_HUMAN
Immunogen Region:	400-458
Immunogen:	Synthetic peptide taken within amino acid region 400-458 on human 5-hydroxytryptamine receptor 2C.

Tissue Specificity	Detected in brain.
Post Translational Modifications	N-glycosylated.
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.
Peptide Name	5-Hydroxytryptamine Receptor 2c 5-Ht-2c 5-Ht2c 5-Htr2c 5-Hydroxytryptamine Receptor 1c 5-Ht-1c 5-Ht1c Serotonin Receptor 2c
Database Links	Reactome: R-HSA-390666 Reactome: R-HSA-416476
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	5-Hydroxytryptamine Receptor 2c protein 5-Ht-2c protein 5-Ht2c protein 5-Htr2c protein 5-Hydroxytryptamine Receptor 1c protein 5-Ht-1c protein 5-Ht1c protein Serotonin Receptor 2c protein HTR2C protein HTR1C protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：5HT2C Receptor Blocking Peptide peptide (STJ505510)