產品詳情
簡單介紹:
ADCY3 Blocking Peptide for STJ502066 peptide (STJ504514)
詳情介紹:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | ADCY3 Blocking Peptide for STJ502066 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | ADCY3 |
Gene ID: | 109 |
Uniprot ID: | ADCY3_HUMAN |
Specificity: | This blocking peptide is recommended for use in combination with ADCY3 antibody, STJ502066 |
Immunogen: | Synthetic peptide corresponding to unique amino acid sequence on human Particulate Adenylyl Cyclase 3 protein. |
Tissue Specificity | Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle. Detected in testis. |
Post Translational Modifications | Sumoylated. Sumoylation is required for targeting ot olfactory cilia. N-glycosylated. Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity. |
Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosesynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet. |
Peptide Name | Adenylate Cyclase Type 3 Atp Pyrophosphate-Lyase 3 Adenylate Cyclase Type Iii Ac-Iii Adenylate Cyclase - Olfactive Type Adenylyl Cyclase 3 Ac3 |
Database Links | Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-381753 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-5610787 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cytoplasm Cell Projection Cilium Golgi Apparatus Also Detected In The Cytoplasm Close To Lipid Droplets |
Alternative Peptide Names | Adenylate Cyclase Type 3 protein Atp Pyrophosphate-Lyase 3 protein Adenylate Cyclase Type Iii protein Ac-Iii protein Adenylate Cyclase - Olfactive Type protein Adenylyl Cyclase 3 protein Ac3 protein ADCY3 protein KIAA0511 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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