ADCY7 Blocking Peptide for STJ502059 peptide (STJ504518) STJ504518-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：ADCY7 Blocking Peptide for STJ502059 peptide (STJ504518)
產品型號：STJ504518-250
產品廠商：ST john's laboratory
產品文檔：

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簡單介紹：

ADCY7 Blocking Peptide for STJ502059 peptide (STJ504518)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	ADCY7 Blocking Peptide for STJ502059 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Adcy7
Gene ID:	11513
Uniprot ID:	ADCY7_MOUSE
Specificity:	This blocking peptide is recommended for use in combination with ADCY7 antibody, STJ502059
Immunogen:	Synthetic peptide corresponding to unique amino acid sequence on mouse Particulate Adenylyl Cyclase 7 protein.

Tissue Specificity	Most abundant in heart, spleen and lung.
Post Translational Modifications	Phosphorylated by PRKCD.
Function	Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G alpha protein with GNA13. Also, during inflammation, mediates zymosan-induced increase intracellular cAMP, leading to protein kinase A pathway activation in order to modulate innate immune responses through heterotrimeric G proteins G(12/13). Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G protein with G beta:gamma complex. Functions, through cAMP response regulation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regulate LPS-induced TNF-alpha production. However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regulating cAMP synthesis in both B and T cells.
Peptide Name	Adenylate Cyclase Type 7 Atp Pyrophosphate-Lyase 7 Adenylate Cyclase Type Vii Adenylyl Cyclase 7
Database Links	Reactome: R-MMU-163615 Reactome: -MMU-170660 Reactome: -MMU-170670 Reactome: -MMU-418597 Reactome: -MMU-5610787
Cellular Localisation	Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	Adenylate Cyclase Type 7 protein Atp Pyrophosphate-Lyase 7 protein Adenylate Cyclase Type Vii protein Adenylyl Cyclase 7 protein Adcy7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：ADCY7 Blocking Peptide for STJ502059 peptide (STJ504518)