產品詳情
簡單介紹:
Anti-AAMP antibody (85-434) (STJ26228)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-AAMP (85-434) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:3000 IF/ICC 1:100-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | AAMP |
Gene ID: | 14 |
Uniprot ID: | AAMP_HUMAN |
Immunogen Region: | 85-434 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 85-434 of human AAMP (NP_001078.2). |
Immunogen Sequence: | VTFALHSASVFCVSLDPKTN TLAVTGGEDDKAFVWRLSDG ELLFECAGHKDSVTCAGFSH DSTLVATGDMSGLLKVWQVD TKEEVWSFEAGDLEWMEWHP RAPVLLAGTADGNTWMWKVP NGDCKTFQGPNCPATCGRVL PDGKRAVVGYEDGTIRIWDL KQGSPIHVLKGTEGHQGPLT CVAANQDGSLILTGSVDCQA KLVSATTGKVVGVFRPETVA SQPSLGEGEESESNSVESL |
Tissue Specificity | Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cytotrophoblasts, and poorly differentiated. colon adenocarcinoma cells found in lymphatics. |
Function | Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway. |
Protein Name | Angio-Associated Migratory Cell Protein |
Database Links | Reactome: R-HSA-168638 Reactome: R-HSA-177929 Reactome: R-HSA-194138 Reactome: R-HSA-428930 |
Cellular Localisation | Cell Membrane Cytoplasm |
Alternative Antibody Names | Anti-Angio-Associated Migratory Cell Protein antibody Anti-AAMP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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