產品詳情
簡單介紹:
Anti-AANAT antibody (STJA0010237)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Serotonin N-acetyltransferase is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 IHC-p 1:50-300 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | AANAT |
Gene ID: | 15 |
Uniprot ID: | SNAT_HUMAN |
Specificity: | This antibody detects endogenous levels of Human, Mouse, Rat SNAT |
Immunogen: | Synthesized peptide derived from human SNAT |
Tissue Specificity | Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. |
Post Translational Modifications | cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. |
Function | Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. |
Protein Name | Serotonin N-Acetyltransferase Serotonin Acetylase Aralkylamine N-Acetyltransferase Aa-Nat |
Database Links | Reactome: R-HSA-209931 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Serotonin N-Acetyltransferase antibody Anti-Serotonin Acetylase antibody Anti-Aralkylamine N-Acetyltransferase antibody Anti-Aa-Nat antibody Anti-AANAT antibody Anti-SNAT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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