產品詳情
簡單介紹:
Artemin protein (STJP000161)
詳情介紹:
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Artemin-protein was developed from. For use in research applications. |
Formulation: | 10 mM Na-citrate; 150 mM NaCl pH 4.5 |
Purification: | Purified from serum-free CHO growth media by ion-exchange chromatography and gel-filtration. Protein is sterile-filtered through 0.22 µm filter |
Concentration: | 1 mg/ml |
Storage Instruction: | Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
Gene Symbol: | ARTN |
Gene ID: | 9048 |
Uniprot ID: | ARTN_HUMAN |
Tissue Specificity | Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain. |
Function | Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. |
Protein Name | Artemin Enovin Neublastin |
Database Links | Reactome: R-HSA-419037 Reactome: R-HSA-5673001 Reactome: R-HSA-8853659 |
Cellular Localisation | Secreted |
Alternative Protein Names | Artemin protein Enovin protein Neublastin protein ARTN protein EVN protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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