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CD48 protein (STJP000144) STJP000144-50|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：CD48 protein (STJP000144)

  • 產品型號：STJP000144-50
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
CD48 protein (STJP000144)
詳情介紹：
Host: CHO cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: CD48-protein was developed from cho cells. For use in research applications.
Formulation: PBS pH 7.4
Purification: Purified by ion-exchange chromatography, hydrophobic interaction chromatography and gel-filtration from serum-free CHO growth media
Concentration: 1 mg/ml
Storage Instruction: Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
Gene Symbol: CD48
Gene ID: 962
Uniprot ID: CD48_HUMAN
Immunogen: Protein contains human CD48 chain (aa 27-220) , propeptide (aa 221-243) is removed
Tissue Specificity Widely expressed on all hematopoietic cells.
Function Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name Cd48 Antigen
B-Lymphocyte Activation Marker Blast-1
Bcm1 Surface Antigen
Leukocyte Antigen Mem-102
Slam Family Member 2
Slamf2
Signaling Lymphocytic Activation Molecule 2
Tct.1
Cd Antigen Cd48
Database Links Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Protein Names Cd48 Antigen protein
B-Lymphocyte Activation Marker Blast-1 protein
Bcm1 Surface Antigen protein
Leukocyte Antigen Mem-102 protein
Slam Family Member 2 protein
Slamf2 protein
Signaling Lymphocytic Activation Molecule 2 protein
Tct.1 protein
Cd Antigen Cd48 protein
CD48 protein
BCM1 protein
BLAST1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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