Annexin A2 Positive Control peptide (Phospho) (STJ504567) STJ504567-5|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Annexin A2 Positive Control peptide (Phospho) (STJ504567)
產品型號：STJ504567-5
產品廠商：ST john's laboratory
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簡單介紹：

Annexin A2 Positive Control peptide (Phospho) (STJ504567)

詳情介紹：

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Phospho-Annexin A2 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.

Dilution Range:	WB: 1:500
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	ANXA2
Gene ID:	302
Uniprot ID:	ANXA2_HUMAN

Post Translational Modifications	Phosphorylation of Tyr-24 enhances heat stress-induced translocations to the cell surface. ISGylated.
Function	Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (Microbial infection) Binds M.pneumoniae CARDS toxin, probably serves as one receptor for this pathogen. When ANXA2 is down-regulated by siRNA, less toxin binds to human cells and less vacuolization (a symptom of M.pneumoniae infection) is seen.
Peptide Name	Annexin A2 Annexin Ii Annexin-2 Calpactin I Heavy Chain Calpactin-1 Heavy Chain Chromobindin-8 Lipocortin Ii Placental Anticoagulant Protein Iv Pap-Iv Protein I P36
Database Links	Reactome: R-HSA-445355 Reactome: R-HSA-6798695 Reactome: R-HSA-75205 Reactome: R-HSA-8950505
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Basement Membrane Melanosome In The Lamina Beneath The Plasma Membrane Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Translocated From The Cytoplasm To The Cell Surface Through A Golgi-Independent Mechanism
Alternative Peptide Names	Annexin A2 protein Annexin Ii protein Annexin-2 protein Calpactin I Heavy Chain protein Calpactin-1 Heavy Chain protein Chromobindin-8 protein Lipocortin Ii protein Placental Anticoagulant Protein Iv protein Pap-Iv protein Protein I protein P36 protein ANXA2 protein ANX2 protein ANX2L4 protein CAL1H protein LPC2D protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Annexin A2 Positive Control peptide (Phospho) (STJ504567)