產品詳情
簡單介紹:
Anti-ABCB5 antibody (Internal) (STJ71387)
詳情介紹:
Host: | Goat |
Applications: | Pep-ELISA/WB/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-ABCB5 (Internal) is suitable for use in ELISA, Western Blot and Flow Cytometry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.3-1µg/ml FC-Flow cytometric analysis of HepG2 cells. 10ug/ml ELISA-antibody detection limit dilution 1:32000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | ABCB5 |
Gene ID: | 340273 |
Uniprot ID: | ABCB5_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_848654.3; NP_001157413.1 |
Specificity: | This antibody is expected to recognise both reported isoforms (NP_848654.3; NP_001157413.1) |
Immunogen Sequence: | QTQHRNTSKKAQ |
Function | Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. |
Protein Name | Atp-Binding Cassette Sub-Family B Member 5 Abcb5 P-Gp P-Glycoprotein Abcb5 |
Database Links | Reactome: R-HSA-382556 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family B Member 5 antibody Anti-Abcb5 P-Gp antibody Anti-P-Glycoprotein Abcb5 antibody Anti-ABCB5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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