產品詳情
簡單介紹：
FAM20A protein (Recombinant) (STJ11104947)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-FAM20A-protein was developed from rabbit. For use in research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S4947RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:2000-1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAM20A |
| Gene ID: | 54757 |
| Uniprot ID: | FA20A_HUMAN |
| Immunogen Region: | 500-600 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human FAM20A (NP_060035.2). |
| Immunogen Sequence: | AIFDFLIGNMDRHHYEMFTK FGDDGFLIHLDNARGFGRHS HDEISILSPLSQCCMIKKKT LLHLQLLAQADYRLSDVMRE SLLEDQLSPVLTEPHLLALD R |
| Tissue Specificity | Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
| Post Translational Modifications | N-glycosylated. |
| Function | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
| Protein Name | Pseudokinase Fam20a |
| Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted Golgi Apparatus Endoplasmic Reticulum |
| Alternative Protein Names | Pseudokinase Fam20a protein FAM20A protein UNQ9388 protein PRO34279 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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