產品詳情
簡單介紹:
Human 4-1BB (CD137) protein (Recombinant) (STJP000593)
詳情介紹:
Host: | CHO cells |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human 4-1BB (CD137)-protein was developed from cho cells. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised 0.2 Mu m filtered PBS solution, pH7.2. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The activity was tested by the ability of immobilized recombinant mouse 4-1BBL to bind human 4-1BB with a linear range of 10-500 ng/ml NA |
Gene Symbol: | TNFRSF9 |
Gene ID: | 3604 |
Uniprot ID: | TNR9_HUMAN |
Immunogen Region: | C-Term |
Immunogen: | Optimized DNA sequence encoding Human 4-1BB (CD137) fused to a C terminal IgG1 Fc tag was expressed in CHO Cells. NA |
Tissue Specificity | Expressed on the surface of activated T-cells. |
Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 9 4-1bb Ligand Receptor Cdw137 T-Cell Antigen 4-1bb Homolog T-Cell Antigen Ila Cd Antigen Cd137 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 9 protein 4-1bb Ligand Receptor protein Cdw137 protein T-Cell Antigen 4-1bb Homolog protein T-Cell Antigen Ila protein Cd Antigen Cd137 protein TNFRSF9 protein CD137 protein ILA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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