Human ADAM 12 protein (Recombinant) (STJP000288) STJP000288|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human ADAM 12 protein (Recombinant) (STJP000288)

詳情介紹：

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human ADAM 12-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Dilution Range:	Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:	The activity was tested by the ability of recombinant human ADAM 12 to cleave recombinant human IGFBP3 NA

Gene Symbol:	ADAM12
Gene ID:	8038
Uniprot ID:	ADA12_HUMAN
Immunogen Region:	ARG29-ASP513
Immunogen:	Optimized DNA sequence encoding mature chain of human ADAM 12 (ARG29-ASP513) including a C-terminal His tag was expressed in HEK293 cells. NA

Tissue Specificity	Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
Post Translational Modifications	The precursor is cleaved by a furin endopeptidase.
Function	Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Protein Name	Disintegrin And Metalloproteinase Domain-Containing Protein 12 Adam 12 Meltrin-Alpha
Database Links	Reactome: R-HSA-177929 Reactome: R-HSA-8941237
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Secreted Isoform 3: Secreted Isoform 4: Secreted
Alternative Protein Names	Disintegrin And Metalloproteinase Domain-Containing Protein 12 protein Adam 12 protein Meltrin-Alpha protein ADAM12 protein MLTN protein UNQ346 protein PRO545 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human ADAM 12 protein (Recombinant) (STJP000288)