產品詳情
簡單介紹:
Anti-ABCD2 antibody (310-390 aa) (STJ190582)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ATP-binding cassette sub-family D member 2 (310-390 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ABCD2 |
Gene ID: | 225 |
Uniprot ID: | ABCD2_HUMAN |
Immunogen Region: | 310-390 aa |
Specificity: | ABCD2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 310-390 |
Function | ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen. Like ABCD1 seems to have fatty acyl-CoA thioesterase (ACOT) and ATPase activities, according to this model, VLCFA-CoA as free VLCFA is transpoted in an ATP-dependent manner into peroxisomes after the hydrolysis of VLCFA-CoA mediated by the ACOT activity of ABCD2 (Probable). Shows overlapping substrate specificities with ABCD1 toward saturated fatty acids (FA) and monounsaturated FA (MUFA) but has a distinct substrate preference for shorter VLCFA (C22:0) and polyunsaturated fatty acid (PUFA) such as C22:6-CoA and C24:6-CoA (in vitro). Thus, may play a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosesynthesis of fatty acids by beta-oxidation. |
Protein Name | Atp-Binding Cassette Sub-Family D Member 2 Adrenoleukodystrophy-Like 1 Adrenoleukodystrophy-Related Protein Haldr |
Database Links | Reactome: R-HSA-1369062 Reactome: R-HSA-9603798 |
Cellular Localisation | Peroxisome Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family D Member 2 antibody Anti-Adrenoleukodystrophy-Like 1 antibody Anti-Adrenoleukodystrophy-Related Protein antibody Anti-Haldr antibody Anti-ABCD2 antibody Anti-ALD1 antibody Anti-ALDL1 antibody Anti-ALDR antibody Anti-ALDRP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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