Anti-ABCD2 antibody (420-500) (STJ118473) STJ118473|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

你添加了1件商品查看購物車

簡單介紹：

Anti-ABCD2 antibody (420-500) (STJ118473)

詳情介紹：

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ABCD2 (420-500) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCD2
Gene ID:	225
Uniprot ID:	ABCD2_HUMAN
Immunogen Region:	420-500
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 420-500 of human ABCD2 (NP_005155.1).
Immunogen Sequence:	TARVYNMFWVFDEVKRGIYK RTAVIQESESHSKNGAKVEL PLSDTLAIKGKVIDVDHGII CENVPIITPAGEVVASRLNF K

Tissue Specificity	Predominantly expressed in brain and heart.
Function	ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen. Like ABCD1 seems to have fatty acyl-CoA thioesterase (ACOT) and ATPase activities, according to this model, VLCFA-CoA as free VLCFA is transpoted in an ATP-dependent manner into peroxisomes after the hydrolysis of VLCFA-CoA mediated by the ACOT activity of ABCD2 (Probable). Shows overlapping substrate specificities with ABCD1 toward saturated fatty acids (FA) and monounsaturated FA (MUFA) but has a distinct substrate preference for shorter VLCFA (C22:0) and polyunsaturated fatty acid (PUFA) such as C22:6-CoA and C24:6-CoA (in vitro). Thus, may play a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosesynthesis of fatty acids by beta-oxidation.
Protein Name	Atp-Binding Cassette Sub-Family D Member 2 Adrenoleukodystrophy-Like 1 Adrenoleukodystrophy-Related Protein Haldr
Database Links	Reactome: R-HSA-1369062 Reactome: R-HSA-9603798
Cellular Localisation	Peroxisome Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family D Member 2 antibody Anti-Adrenoleukodystrophy-Like 1 antibody Anti-Adrenoleukodystrophy-Related Protein antibody Anti-Haldr antibody Anti-ABCD2 antibody Anti-ALD1 antibody Anti-ALDL1 antibody Anti-ALDR antibody Anti-ALDRP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：Anti-ABCD2 antibody (420-500) (STJ118473)