Anti-ABCD3 antibody (340-475) (STJ11100138) STJ11100138|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-ABCD3 antibody (340-475) (STJ11100138)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ABCD3 (340-475) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCD3
Gene ID:	5825
Uniprot ID:	ABCD3_HUMAN
Immunogen Region:	340-475
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 340-475 of human PMP70/ABCD3 (NP_002849.1).
Immunogen Sequence:	LSHPRHLKSTHSELLEDYYQ SGRMLLRMSQALGRIVLAGR EMTRLAGFTARITELMQVLK DLNHGKYERTMVSQQEKGIE GVQVIPLIPGAGEIIIADNI IKFDHVPLATPNGDVLIRDL NFEVRSGANVLICGPN

Post Translational Modifications	Ubiquitinated by PEX2 during pexophagy in response to starvation, leading to its degradation.
Function	Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosesynthesis of fatty acids by beta-oxidation.
Protein Name	Atp-Binding Cassette Sub-Family D Member 3 70 Kda Peroxisomal Membrane Protein Pmp70
Database Links	Reactome: R-HSA-1369062 Reactome: R-HSA-8980692 Reactome: R-HSA-9013106 Reactome: R-HSA-9603798
Cellular Localisation	Peroxisome Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family D Member 3 antibody Anti-70 Kda Peroxisomal Membrane Protein antibody Anti-Pmp70 antibody Anti-ABCD3 antibody Anti-PMP70 antibody Anti-PXMP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ABCD3 antibody (340-475) (STJ11100138)