產品詳情
簡單介紹:
Anti-ABCD4 antibody (100-280) (STJ119616)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ABCD4 (100-280) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ABCD4 |
Gene ID: | 5826 |
Uniprot ID: | ABCD4_HUMAN |
Immunogen Region: | 100-280 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-280 of human ABCD4 (NP_005041.1). |
Immunogen Sequence: | DQFTCNLLYVSWRKDLTEHL HRLYFRGRAYYTLNVLRDDI DNPDQRISQDVERFCRQLSS MASKLIISPFTLVYYTYQCF QSTGWLGPVSIFGYFILGTV VNKTLMGPIVMKLVHQEKLE GDFRFKHMQIRVNAEPAAFY RAGHVEHMRTDRRLQRLLQT QRELMSKELWLYIGINTFDY L |
Tissue Specificity | Ubiquitous. |
Function | Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane. |
Protein Name | Lysosomal Cobalamin Transporter Abcd4 Atp-Binding Cassette Sub-Family D Member 4 Pmp70-Related Protein P70r Peroxisomal Membrane Protein 1-Like Pxmp1-L Peroxisomal Membrane Protein 69 Pmp69 |
Database Links | Reactome: R-HSA-5683329 Reactome: R-HSA-9758881 Reactome: R-HSA-9758890 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Lysosome Membrane Targeted By Lmbrd1 Lysosomal Chaperone To The Lysosomal Membrane |
Alternative Antibody Names | Anti-Lysosomal Cobalamin Transporter Abcd4 antibody Anti-Atp-Binding Cassette Sub-Family D Member 4 antibody Anti-Pmp70-Related Protein antibody Anti-P70r antibody Anti-Peroxisomal Membrane Protein 1-Like antibody Anti-Pxmp1-L antibody Anti-Peroxisomal Membrane Protein 69 antibody Anti-Pmp69 antibody Anti-ABCD4 antibody Anti-PXMP1L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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