產品詳情
簡單介紹:
Human AFP (HLA-A*02:01) Complex protein (Recombinant) (C-His & Avi) (STJP002350)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human AFP (HLA-A*02:01) Complex-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Endotoxin: | Less than 1EU per Mu g by the LAL method. |
Gene Symbol: | B2M |
Gene ID: | 567 |
Uniprot ID: | B2MG_HUMAN |
Immunogen Region: | Gly25-Thr305 (HLA-A*02:01) , Ile21-Met119 (B2M) and PLFQVPEPV |
Immunogen: | Recombinant Human AFP (HLA-A*02:01) Complex Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.;It contains Gly25-Thr305 (HLA-A*02:01) , Ile21-Met119 (B2M) and PLFQVPEPV peptide. |
Function | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. |
Protein Name | Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 |
Database Links | Reactome: R-HSA-1236974 Reactome: R-HSA-1236977 Reactome: R-HSA-164940 Reactome: R-HSA-198933 Reactome: R-HSA-2172127 Reactome: R-HSA-2424491 Reactome: R-HSA-6798695 Reactome: R-HSA-877300 Reactome: R-HSA-9637628 Reactome: R-HSA-9705671 Reactome: R-HSA-977225 Reactome: R-HSA-983170 |
Cellular Localisation | Secreted Cell Surface Detected In Serum And Urine (Microbial Infection) In The Presence Of M Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface |
Alternative Protein Names | Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 protein B2M protein CDABP0092 protein HDCMA22P protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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