Human Aminopeptidase N/CD13 protein (Recombinant) (C-His) (STJP002597) STJP002597|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Human Aminopeptidase N/CD13 protein (Recombinant) (C-His) (STJP002597)
產品型號：STJP002597
產品廠商：ST john's laboratory
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Human Aminopeptidase N/CD13 protein (Recombinant) (C-His) (STJP002597)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Aminopeptidase N/CD13-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:	Measured by its ability to cleave the fluorogenic peptide substrate, Ala-7-amido-4-methylcoumarin (Ala-AMC). The specific activity is >4300 pmol/min/Mu g.

Gene Symbol:	ANPEP
Gene ID:	290
Uniprot ID:	AMPN_HUMAN
Immunogen Region:	Lys69-Lys967
Immunogen:	Recombinant Human Aminopeptidase N/CD13 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys69-Lys967) of human ANPEP/CD13 (Accession #NP_001141.2) fused with an 8×His tag at the C-terminus.

Post Translational Modifications	Sulfated. N- and O-glycosylated. May undergo proteolysis and give rise to a soluble form.
Function	Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. (Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. (Microbial infection) Mediates as well Human cytomegalovirus (HCMV) infection.
Protein Name	Aminopeptidase N Ap-N Hapn Alanyl Aminopeptidase Aminopeptidase M Ap-M Microsomal Aminopeptidase Myeloid Plasma Membrane Glycoprotein Cd13 Gp150 Cd Antigen Cd13
Database Links	Reactome: R-HSA-2022377 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Also Found As A Soluble Form
Alternative Protein Names	Aminopeptidase N protein Ap-N protein Hapn protein Alanyl Aminopeptidase protein Aminopeptidase M protein Ap-M protein Microsomal Aminopeptidase protein Myeloid Plasma Membrane Glycoprotein Cd13 protein Gp150 protein Cd Antigen Cd13 protein ANPEP protein APN protein CD13 protein PEPN protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human Aminopeptidase N/CD13 protein (Recombinant) (C-His) (STJP002597)