Human Angiopoietin-2 protein (Recombinant) (STJP000283) STJP000283|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human Angiopoietin-2 protein (Recombinant) (STJP000283)

詳情介紹：

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Angiopoietin-2-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:	The activity was tested by the ability of immobilized recombinant Human Tie2 to bind biotinylated recombinant human Angiopoietin-2 in ELISA NA

Gene Symbol:	ANGPT2
Gene ID:	285
Uniprot ID:	ANGP2_HUMAN
Immunogen Region:	ECD
Immunogen:	Optimized DNA sequence encoding extracellular domain of Human Angiopoietin-2 including a C-terminal His tag was expressed in HEK293 cells. NA

Function	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.
Protein Name	Angiopoietin-2 Ang-2
Database Links	Reactome: R-HSA-210993
Cellular Localisation	Secreted
Alternative Protein Names	Angiopoietin-2 protein Ang-2 protein ANGPT2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human Angiopoietin-2 protein (Recombinant) (STJP000283)