BMP1 Blocking Peptide peptide (STJ503725) STJ503725-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：BMP1 Blocking Peptide peptide (STJ503725)
產品型號：STJ503725-250
產品廠商：ST john's laboratory
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BMP1 Blocking Peptide peptide (STJ503725)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	BMP1 Blocking Peptide is synthetically produced from the 1-50 aa sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	BMP1
Gene ID:	649
Uniprot ID:	BMP1_HUMAN
Immunogen Region:	1-50 aa
Immunogen:	Synthetic peptide taken within amino acid region 1-50 on human BMP1 protein.

Tissue Specificity	Ubiquitous.
Post Translational Modifications	Proteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion.
Function	Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation. Isoform BMP1-3: Plays an important role in bone repair by acting as a coactivator of BMP7.
Peptide Name	Bone Morphogenetic Protein 1 Bmp-1 Mammalian Tolloid Protein Mtld Procollagen C-Proteinase Pcp
Database Links	Reactome: R-HSA-1474228 Reactome: R-HSA-1650814 Reactome: R-HSA-2214320 Reactome: R-HSA-2243919 Reactome: R-HSA-8963896 P13497-3
Cellular Localisation	Golgi Apparatus Trans-Golgi Network Secreted Extracellular Space Extracellular Matrix Co-Localizes With Postn In The Golgi Isoform Bmp1-3: Secreted
Alternative Peptide Names	Bone Morphogenetic Protein 1 protein Bmp-1 protein Mammalian Tolloid Protein protein Mtld protein Procollagen C-Proteinase protein Pcp protein BMP1 protein PCOLC protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：BMP1 Blocking Peptide peptide (STJ503725)