產品詳情
簡單介紹:
Anti-ABCG4 antibody (540-620 aa) (STJ190585)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ATP-binding cassette sub-family G member 4 (540-620 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ABCG4 |
Gene ID: | 64137 |
Uniprot ID: | ABCG4_HUMAN |
Immunogen Region: | 540-620 aa |
Specificity: | ABCG4 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 540-620 |
Function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that may be involved in the cellular efflux of sterols, in particular cholesterol and desmosterol (a cholesterol precursor), to high-density lipoprotein (HDL). May play an important role in the removal of amyloid-beta peptides from brain, in a process that can be antagonized by desmosterol. However it is unclear whether ABCG4 can directly transport amyloid-beta peptides or whether peptide export may be facilitated due to changes in the membrane lipid environment. Induces apoptosis in various cells. |
Protein Name | Atp-Binding Cassette Sub-Family G Member 4 |
Database Links | Reactome: R-HSA-1369062 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cytoplasmic Vesicle Membrane Endosome Membrane |
Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family G Member 4 antibody Anti-ABCG4 antibody Anti-WHITE2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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