產品詳情
簡單介紹:
Anti-ABCG8 antibody (1-320) (STJ22469)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ABCG8 (1-320) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ABCG8 |
Gene ID: | 64241 |
Uniprot ID: | ABCG8_HUMAN |
Immunogen Region: | 1-320 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human ABCG8 (NP_071882.1). |
Immunogen Sequence: | MAGKAAEERGLPKGATPQDT SGLQDRLFSSESDNSLYFTY SGQPNTLEVRDLNYQVDLAS QVPWFEQLAQFKMPWTSPSC QNSCELGIQNLSFKVRSGQM LAIIGSSGCGRASLLDVITG RGHGGKIKSGQIWINGQPSS PQLVRKCVAHVRQHNQLLPN LTVRETLAFIAQMRLPRTFS QAQRDKRVEDVIAELRLRQC ADTRVGNMYVRGLSGGERRR VSIGVQLLWNPGILILDEP |
Tissue Specificity | Predominantly expressed in the liver. Low expression levels in the small intestine and colon. Very low levels in other tissues, including brain, heart and spleen. |
Post Translational Modifications | N-glycosylated. |
Function | ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG5 has ATPase activity. |
Protein Name | Atp-Binding Cassette Sub-Family G Member 8 Sterolin-2 |
Database Links | Reactome: R-HSA-1369062 Reactome: R-HSA-5679090 Reactome: R-HSA-5679096 Reactome: R-HSA-9029569 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane |
Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family G Member 8 antibody Anti-Sterolin-2 antibody Anti-ABCG8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
相關信息

- 細胞培養玄學-MRC-5細胞 2025-01-07
- Ocean NanoTech定製的詳細步驟 2021-10-31
- LaysanBio代理商相關文獻資料2020 2021-10-31
- click chemistry tools數據結果比... 2021-10-31
- Abbiotec代理的產品得到重複驗證2020 2021-10-31
- zyagen Laboratories代理的產品得到... 2021-06-20
- Toxin Technologies代理商相關文獻資... 2021-03-14
- 熱烈祝賀91麻豆福利视频网生物正式代理biocolor公司試劑產品... 2021-03-14
- 熱烈祝賀91麻豆福利视频网生物正式代理cytognos公司試劑產品... 2021-03-14
- Gelest代理的產品得到重複驗證2020 2021-03-14