產品詳情
簡單介紹：
Anti-ABHD12 antibody (231-280 aa) (STJ91420)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Lysophosphatidylserine lipase ABHD12 (231-280 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABHD12 |
| Gene ID: | 26090 |
| Uniprot ID: | ABD12_HUMAN |
| Immunogen Region: | 231-280 aa |
| Specificity: | ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ABHD12 at the amino acid range 231-280 |
| Function | Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes. Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system. Also able to hydrolyze oxidized phosphatidylserine.oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways. Has a strong preference for very-long-chain lipid substrates.substrate specificity is likely due to improved catalysis and not improved substrate binding. |
| Protein Name | Lysophosphatidylserine Lipase Abhd12 2-Arachidonoylglycerol Hydrolase Abhd12 Abhydrolase Domain-Containing Protein 12 Habhd12 Monoacylglycerol Lipase Abhd12 Oxidized Phosphatidylserine Lipase Abhd12 |
| Database Links | Reactome: R-HSA-426048 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Lysophosphatidylserine Lipase Abhd12 antibody Anti-2-Arachidonoylglycerol Hydrolase Abhd12 antibody Anti-Abhydrolase Domain-Containing Protein 12 antibody Anti-Habhd12 antibody Anti-Monoacylglycerol Lipase Abhd12 antibody Anti-Oxidized Phosphatidylserine Lipase Abhd12 antibody Anti-ABHD12 antibody Anti-C20orf22 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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