產品詳情
簡單介紹：
Anti-ABHD2 antibody (251-300 aa) (STJ91424)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Monoacylglycerol lipase ABHD2 (251-300 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABHD2 |
| Gene ID: | 11057 |
| Uniprot ID: | ABHD2_HUMAN |
| Immunogen Region: | 251-300 aa |
| Specificity: | ABHD2 Polyclonal Antibody detects endogenous levels of ABHD2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ABHD2 at the amino acid range 251-300 |
| Function | Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. May also play a role in smooth muscle cells migration. |
| Protein Name | Monoacylglycerol Lipase Abhd2 2-Arachidonoylglycerol Hydrolase Abhydrolase Domain-Containing Protein 2 Acetylesterase Lung Alpha/Beta Hydrolase 2 Progesterone-Sensitive Lipase Protein Phps1-2 |
| Cellular Localisation | Cell Projection Cilium Flagellum Membrane Single-Pass Type Ii Membrane Protein Cell Membrane |
| Alternative Antibody Names | Anti-Monoacylglycerol Lipase Abhd2 antibody Anti-2-Arachidonoylglycerol Hydrolase antibody Anti-Abhydrolase Domain-Containing Protein 2 antibody Anti-Acetylesterase antibody Anti-Lung Alpha/Beta Hydrolase 2 antibody Anti-Progesterone-Sensitive Lipase antibody Anti-Protein Phps1-2 antibody Anti-ABHD2 antibody Anti-LABH2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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