產品詳情
簡單介紹:
Human BAFF-R (CD268) protein (Recombinant) (STJP000674)
詳情介紹:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human BAFF-R (CD268)-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered solution in 0.5% glycine, 0.5% sucrose,.01% Tween80, mM Glutamic acid, pH7.5. |
Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: | Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The ED (50) was determined by the ability to block BAFF induced survival of splenocyte cells, and was found to be in the range of.0-5.0 ug/ml. NA |
Gene Symbol: | TNFRSF13C |
Gene ID: | 115650 |
Uniprot ID: | TR13C_HUMAN |
Immunogen Region: | ECD |
Immunogen: | DNA sequence encoding Human BAFF-R extracellular domain was expressed in HEK293 cells NA |
Immunogen Sequence: | MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPGLL FG APALLGLALV LALVLVGLVS WRRRQRRLRG ASSAEAPDGD NA |
Tissue Specificity | Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes. |
Function | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 13c B-Cell-Activating Factor Receptor Baff Receptor Baff-R Blys Receptor 3 Cd Antigen Cd268 |
Database Links | Reactome: R-HSA-5668541 Reactome: R-HSA-5676594 |
Cellular Localisation | Membrane Single-Pass Type Iii Membrane Protein |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 13c protein B-Cell-Activating Factor Receptor protein Baff Receptor protein Baff-R protein Blys Receptor 3 protein Cd Antigen Cd268 protein TNFRSF13C protein BAFFR protein BR3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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