Human basic FGF protein (Recombinant) (Plant derived) (STJP001806) STJP001806-5|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Human basic FGF protein (Recombinant) (Plant derived) (STJP001806)
產品型號：STJP001806-5
產品廠商：ST john's laboratory
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簡單介紹：

Human basic FGF protein (Recombinant) (Plant derived) (STJP001806)

詳情介紹：

Host:	Cereal grain NA
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human basic FGF-Plant derived protein was developed from cereal grain and has a target region of Plant derived. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilised from 0.2 Mu m filtered solution inM NaCl, 20mM PB pH7.0. NA
Dilution Range:	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than.1 mg/mL. This solution can then be diluted into other buffers. NA
Storage Instruction:	The lyophilized protein is stable for at least years from date of receipt at-20°C C. Upon reconstitution, this cytokine can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA

Gene Symbol:	FGF2
Gene ID:	2247
Uniprot ID:	FGF2_HUMAN
Immunogen Region:	Mature chain
Immunogen:	DNA sequence encoding Human basic Fibroblast Growth Factor mature chain was expressed in Cereal Grain. NA
Immunogen Sequence:	MAAGSITTLP ALPEDGGSGA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHI KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTDE CFFFERLESN NYNTYRSRKY TSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS NA

Post Translational Modifications	Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion. Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.
Function	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation.
Protein Name	Fibroblast Growth Factor 2 Fgf-2 Basic Fibroblast Growth Factor Bfgf Heparin-Binding Growth Factor 2 Hbgf-2
Database Links	Reactome: R-HSA-109704 Reactome: R-HSA-1257604 Reactome: R-HSA-1839122 Reactome: R-HSA-1839130 Reactome: R-HSA-190322 Reactome: R-HSA-190370 Reactome: R-HSA-190372 Reactome: R-HSA-190373 Reactome: R-HSA-190375 Reactome: R-HSA-190377 Reactome: R-HSA-2033519 Reactome: R-HSA-2219530 Reactome: R-HSA-2892247 Reactome: R-HSA-3000170 Reactome: R-HSA-3000171 Reactome: R-HSA-5654219 Reactome: R-HSA-5654221 Reactome: R-HSA-5654227 Reactome: R-HSA-5654228 Reactome: R-HSA-5654687 Reactome: R-HSA-5654688 Reactome: R-HSA-5654689 Reactome: R-HSA-5654693 Reactome: R-HSA-5654695 Reactome: R-HSA-5654699 Reactome: R-HSA-5654700 Reactome: R-HSA-5654704 Reactome: R-HSA-5654706 Reactome: R-HSA-5654710 Reactome: R-HSA-5654712 Reactome: R-HSA-5654719 Reactome: R-HSA-5654720 Reactome: R-HSA-5654726 Reactome: R-HSA-5654727 Reactome: R-HSA-5654732 Reactome: R-HSA-5654733 Reactome: R-HSA-5655253 Reactome: R-HSA-5655302 Reactome: R-HSA-5655332 Reactome: R-HSA-5658623 Reactome: R-HSA-5673001 Reactome: R-HSA-6785807 Reactome: R-HSA-6811558 Reactome: R-HSA-8851708 Reactome: R-HSA-9761174
Cellular Localisation	Secreted Nucleus Exported From Cells By An Endoplasmic Reticulum (Er)/Golgi-Independent Mechanism Unconventional Secretion Of Fgf2 Occurs By Direct Translocations Across The Plasma Membrane Binding Of Exogenous Fgf2 To Fgfr Facilitates Endocytosis Followed By Translocations Of Fgf2 Across Endosomal Membrane Into The Cytosol Nuclear Import From The Cytosol Requires The Classical Nuclear Import Machinery Involving Proteins Kpna1 And Kpnb1 As Well As Cep57
Alternative Protein Names	Fibroblast Growth Factor 2 protein Fgf-2 protein Basic Fibroblast Growth Factor protein Bfgf protein Heparin-Binding Growth Factor 2 protein Hbgf-2 protein FGF2 protein FGFB protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human basic FGF protein (Recombinant) (Plant derived) (STJP001806)