產品詳情
簡單介紹:
Human BCMA (CD269) protein (Recombinant) (STJP000587)
詳情介紹:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human BCMA (CD269)-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered mm Tris solution pH7.5. |
Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: | Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The ED (50) was determined by the ability to bind immobilized recombinant Human BAFF and was calculated to beng/ml. NA |
Gene Symbol: | TNFRSF17 |
Gene ID: | 608 |
Uniprot ID: | TNR17_HUMAN |
Immunogen Region: | ECD |
Immunogen: | Optimized DNA sequence encoding Human BCMA extracellular domain sp|Q02223|1-54 fused to C terminal Human IgG1 Fc His tag was expressed in HEK293 Cells. NA |
Immunogen Sequence: | MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNA ILWTCL NA |
Tissue Specificity | Expressed in mature B-cells, but not in T-cells or monocytes. |
Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 17 B-Cell Maturation Protein Cd Antigen Cd269 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Cell Membrane Single-Pass Type Iii Membrane Protein Endomembrane System Perinuclear Golgi-Like Structures |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 17 protein B-Cell Maturation Protein protein Cd Antigen Cd269 protein TNFRSF17 protein BCM protein BCMA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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