Human Beta-2-microglobulin/B2M protein (Recombinant) (C-His) (STJP000881) STJP000881|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human Beta-2-microglobulin/B2M protein (Recombinant) (C-His) (STJP000881)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Beta-2-microglobulin/B2M-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human B2M at 2 Mu g/mL (100 Mu L/well) can bind Recombinant Human CD8 alpha with a linear range of 31.25-341 ng/mL.

Gene Symbol:	B2M
Gene ID:	567
Uniprot ID:	B2MG_HUMAN
Immunogen:	Recombinant Human Beta-2-microglobulin/B2M Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ile21-Met119) of human B2M/Beta-2-microglobulin (Accession #NP_004039.1) fused with a 6×His tag at the C-termin

Post Translational Modifications	Glycation of Ile-21 is observed in long-term hemodialysis patients.
Function	Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name	Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links	Reactome: R-HSA-1236974 Reactome: R-HSA-1236977 Reactome: R-HSA-164940 Reactome: R-HSA-198933 Reactome: R-HSA-2172127 Reactome: R-HSA-2424491 Reactome: R-HSA-6798695 Reactome: R-HSA-877300 Reactome: R-HSA-9637628 Reactome: R-HSA-9705671 Reactome: R-HSA-977225 Reactome: R-HSA-983170
Cellular Localisation	Secreted Cell Surface Detected In Serum And Urine (Microbial Infection) In The Presence Of M Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Protein Names	Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 protein B2M protein CDABP0092 protein HDCMA22P protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human Beta-2-microglobulin/B2M protein (Recombinant) (C-His) (STJP000881)