產品詳情
簡單介紹:
BMPR1A Positive Control for STJ500281 peptide (STJ505491)
詳情介紹:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | BMPR1A Positive Control for STJ500281 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | BMPR1A |
Gene ID: | 657 |
Uniprot ID: | BMR1A_HUMAN |
Specificity: | This is positive control is recommended for use in combination with BMPR1A antibody STJ500281. |
Tissue Specificity | Highly expressed in skeletal muscle. |
Post Translational Modifications | Glycosylated. |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2. |
Peptide Name | Bone Morphogenetic Protein Receptor Type-1a Bmp Type-1a Receptor Bmpr-1a Activin Receptor-Like Kinase 3 Alk-3 Serine/Threonine-Protein Kinase Receptor R5 Skr5 Cd Antigen Cd292 |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Surface |
Alternative Peptide Names | Bone Morphogenetic Protein Receptor Type-1a protein Bmp Type-1a Receptor protein Bmpr-1a protein Activin Receptor-Like Kinase 3 protein Alk-3 protein Serine/Threonine-Protein Kinase Receptor R5 protein Skr5 protein Cd Antigen Cd292 protein BMPR1A protein ACVRLK3 protein ALK3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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