產品詳情
簡單介紹:
BTB/POZ domain-containing protein 7 Blocking Peptide peptide (STJ503735)
詳情介紹:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | BTB/POZ domain-containing protein 7 Blocking Peptide is synthetically produced from the 1050-1150 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | BTBD7 |
Gene ID: | 55727 |
Uniprot ID: | BTBD7_HUMAN |
Immunogen Region: | 1050-1150 |
Immunogen: | Synthetic peptide taken within amino acid region 1050-1150 on human BTBD7 protein. |
Function | Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. |
Peptide Name | Btb/Poz Domain-Containing Protein 7 |
Cellular Localisation | Nucleus |
Alternative Peptide Names | Btb/Poz Domain-Containing Protein 7 protein BTBD7 protein KIAA1525 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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