Human BMPR-1B/ALK-6 protein (Recombinant) (C-hFc&His) (STJP001235) STJP001235|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human BMPR-1B/ALK-6 protein (Recombinant) (C-hFc&His) (STJP001235)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human BMPR-1B/ALK-6-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Human BMP2 at 4 Mu g/mL (100 Mu L/well) can bind Human BMPRIB with a linear range of 20-338 ng/mL.2. Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production

Gene Symbol:	BMPR1B
Gene ID:	658
Uniprot ID:	BMR1B_HUMAN
Immunogen:	Active Recombinant Human BMPR-1B/ALK-6 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys14-Arg126) of human BMPR-IB/ALK-6 (Accession #NP_001194.1) fused with a Fc, 6×His tag at the C-terminus.

Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Protein Name	Bone Morphogenetic Protein Receptor Type-1b Bmp Type-1b Receptor Bmpr-1b Cd Antigen Cdw293
Database Links	Reactome: R-HSA-201451
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Bone Morphogenetic Protein Receptor Type-1b protein Bmp Type-1b Receptor protein Bmpr-1b protein Cd Antigen Cdw293 protein BMPR1B protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human BMPR-1B/ALK-6 protein (Recombinant) (C-hFc&amp;His) (STJP001235)