產品詳情
簡單介紹:
Human cAspAT/AATC/GOT1 protein (Recombinant) (No tag) (STJP000815)
詳情介紹:
Host: | E. coli |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human cAspAT/AATC/GOT1-No tag protein was developed from e. coli and has a target region of No tag. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: | GOT1 |
Gene ID: | 2805 |
Uniprot ID: | AATC_HUMAN |
Immunogen: | Recombinant Human cAspAT/AATC/GOT1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala2-Gln413) of human cAspAT (Accession #NP_002070.1). |
Function | Biosesynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. In addition, catalyzes (2S)-2-aminobutanoate, a by-product in the cysteine biosesynthesis pathway. |
Protein Name | Aspartate Aminotransferase - Cytoplasmic Caspat Cysteine Aminotransferase - Cytoplasmic Cysteine Transaminase - Cytoplasmic Ccat Glutamate Oxaloacetate Transaminase 1 Transaminase A |
Database Links | Reactome: R-HSA-1237112 Reactome: R-HSA-70263 Reactome: R-HSA-8963693 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Aspartate Aminotransferase - Cytoplasmic protein Caspat protein Cysteine Aminotransferase - Cytoplasmic protein Cysteine Transaminase - Cytoplasmic protein Ccat protein Glutamate Oxaloacetate Transaminase 1 protein Transaminase A protein GOT1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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