Human Cathepsin B protein (Recombinant) (C-His) (STJP002444) STJP002444|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human Cathepsin B protein (Recombinant) (C-His) (STJP002444)

詳情介紹：

Host:	HEK293 Cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Cathepsin B-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CTSB
Gene ID:	1508
Uniprot ID:	CATB_HUMAN
Immunogen Region:	Arg18-Ile339
Immunogen:	Recombinant Human Cathepsin B Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Arg18-Ile339) of human Cathepsin B (Accession #NP_001899.1) fused with a 6×His tag at the C-terminus.

Function	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Protein Name	Cathepsin B App Secretase Apps Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1679131 Reactome: R-HSA-2022090 Reactome: R-HSA-2132295 Reactome: R-HSA-6798695
Cellular Localisation	Lysosome Melanosome Secreted Extracellular Space Apical Cell Membrane Peripheral Membrane Protein Extracellular Side Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Protein Names	Cathepsin B protein App Secretase protein Apps protein Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain protein CTSB protein CPSB protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human Cathepsin B protein (Recombinant) (C-His) (STJP002444)