Human Cathepsin B protein (Recombinant) (STJP000382) STJP000382|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

你添加了1件商品查看購物車

簡單介紹：

Human Cathepsin B protein (Recombinant) (STJP000382)

詳情介紹：

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Cathepsin B-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilized from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Dilution Range:	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. NA
Storage Instruction:	Recombinant Cathepsin B can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:	The activity was tested by the ability to cleave a flourogenic substrate, the measured activity is 3 nM/ug/min

Gene Symbol:	CTSB
Gene ID:	1508
Uniprot ID:	CATB_HUMAN
Immunogen Region:	ARG18-ILE339
Immunogen:	Optimized DNA sequence encoding mature chain of human Cathepsin B (ARG18-ILE339) including a C-terminal His tag was expressed in HEK293 cells. NA

Tissue Specificity	Expressed in the stratum spinosum of the epidermis. Weak expression is detected in the stratum granulosum.
Function	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Protein Name	Cathepsin B App Secretase Apps Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1679131 Reactome: R-HSA-2022090 Reactome: R-HSA-2132295 Reactome: R-HSA-6798695
Cellular Localisation	Lysosome Melanosome Secreted Extracellular Space Apical Cell Membrane Peripheral Membrane Protein Extracellular Side Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Protein Names	Cathepsin B protein App Secretase protein Apps protein Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain protein CTSB protein CPSB protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：Human Cathepsin B protein (Recombinant) (STJP000382)