Calcium Sensing Receptor Blocking Peptide peptide (STJ503774) STJ503774-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

你添加了1件商品查看購物車

簡單介紹：

Calcium Sensing Receptor Blocking Peptide peptide (STJ503774)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Calcium Sensing Receptor Blocking Peptide is synthetically produced from the 47-69 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	CASR
Gene ID:	846
Uniprot ID:	CASR_HUMAN
Immunogen Region:	47-69
Immunogen:	Synthetic peptide corresponding to amino acids 47-69 on human CASR gene. Sequence: KDQDLKSRPESVECIRYNFRGFR

Tissue Specificity	Expressed in the temporal lobe, frontal lobe, parietal lobe, hippocampus, and cerebellum. Also found in kidney, lung, liver, heart, skeletal muscle, placenta.
Post Translational Modifications	N-glycosylated. Ubiquitinated by RNF19A.which induces proteasomal degradation.
Function	G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as Trp or Phe, act concertedly with divalent cations, such as calcium or magnesium, to achieve full receptor activation.
Peptide Name	Extracellular Calcium-Sensing Receptor Car Casr Hcasr Parathyroid Cell Calcium-Sensing Receptor 1 Pcar1
Database Links	Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-420499
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	Extracellular Calcium-Sensing Receptor protein Car protein Casr protein Hcasr protein Parathyroid Cell Calcium-Sensing Receptor 1 protein Pcar1 protein CASR protein GPRC2A protein PCAR1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：Calcium Sensing Receptor Blocking Peptide peptide (STJ503774)