AKR1B1 Blocking Peptide for STJ500067 peptide (STJ503635) STJ503635-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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AKR1B1 Blocking Peptide for STJ500067 peptide (STJ503635)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	AKR1B1 Blocking Peptide for STJ500067 is synthetically produced from the 250-350 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	AKR1B1
Gene ID:	231
Uniprot ID:	ALDR_HUMAN
Immunogen Region:	250-350
Specificity:	This blocking peptide is recommended for use in combination with AKR1B1 antibody, STJ500067
Immunogen:	Synthetic peptide taken within amino acid region 250-350 on human Aldo-keto reductase family 1, member B1 protein.

Tissue Specificity	Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.
Function	Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates. Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia. Reduces steroids and their derivatives and prostaglandins. Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2-(5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides. Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls).
Peptide Name	Aldo-Keto Reductase Family 1 Member B1 Aldehyde Reductase Aldose Reductase Ar
Database Links	Reactome: R-HSA-196108 Reactome: R-HSA-5652227
Cellular Localisation	Cytoplasm
Alternative Peptide Names	Aldo-Keto Reductase Family 1 Member B1 protein Aldehyde Reductase protein Aldose Reductase protein Ar protein AKR1B1 protein ALDR1 protein ALR2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：AKR1B1 Blocking Peptide for STJ500067 peptide (STJ503635)