产品详情

  • 产品名称：Anti-ABCG1 antibody (560-640 aa) (STJ96425)

  • 产品型号：STJ96425
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ABCG1 antibody (560-640 aa) (STJ96425)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ATP-binding cassette sub-family G member 1 (560-640 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCG1
Gene ID: 9619
Uniprot ID: ABCG1_HUMAN
Immunogen Region: 560-640 aa
Specificity: ABCG1 Polyclonal Antibody detects endogenous levels of ABCG1 protein.
Immunogen: Synthesized peptide derived from ABCG1 at the amino acid range 560-640
Post Translational Modifications Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum.
Function Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol.
Protein Name Atp-Binding Cassette Sub-Family G Member 1
Atp-Binding Cassette Transporter 8
White Protein Homolog
Database Links Reactome: R-HSA-1369062
Reactome: R-HSA-8964058
Reactome: R-HSA-9029569
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Cell Membrane
Predominantly Localized In The Intracellular Compartments Mainly Associated With The Endoplasmic Reticulum (Er) And Golgi Membranes
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family G Member 1 antibody
Anti-Atp-Binding Cassette Transporter 8 antibody
Anti-White Protein Homolog antibody
Anti-ABCG1 antibody
Anti-ABC8 antibody
Anti-WHT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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