产品详情

  • 产品名称：EDG8 Blocking Peptide for STJ502857 peptide (STJ504879)

  • 产品型号：STJ504879-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
EDG8 Blocking Peptide for STJ502857 peptide (STJ504879)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: EDG8 Blocking Peptide for STJ502857 is synthetically produced from the 380-400 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: S1pr5
Gene ID: 60399
Uniprot ID: S1PR5_RAT
Immunogen Region: 380-400
Specificity: This blocking peptide is recommended for use in combination with EDG8 antibody, STJ502857
Immunogen: Synthetic peptide taken within amino acid region 380-400 of rat S1P5R/EDG8 protein.
Tissue Specificity Found almost exclusively in brain and skin. Ubiquitously detected in different brain regions with very prominent expression in lower brain regions such as the midbrain, pons, medulla, and spinal cord. Expressed predominantly within white matter tracts of the brain. Corpus callosum, optic nerve, olfactory tract, anterior commissure, internal and external capsules, fimbra of the hippocampus, mammillary tract, stria medullaris, and white matter of the cerebellum and brain stem all express the receptor. Within the striatum itself white matter fascicles express the receptor. Detected also in spleen and lung. Not observed in heart, liver, skeletal muscle, kidney, or testes.
Function Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins. Displays antiproliferative effects in transfected CHO-K1 and HEK293 cells.
Peptide Name Sphingosine 1-Phosphate Receptor 5
S1p Receptor 5
S1p5
Endothelial Differentiation G-Protein-Coupled Receptor 8
Nerve Growth Factor-Regulated G-Protein-Coupled Receptor 1
Nrg-1
Sphingosine 1-Phosphate Receptor Edg-8
S1p Receptor Edg-8
Database Links Reactome: R-RNO-418594
Reactome: -RNO-419408
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Sphingosine 1-Phosphate Receptor 5 protein
S1p Receptor 5 protein
S1p5 protein
Endothelial Differentiation G-Protein-Coupled Receptor 8 protein
Nerve Growth Factor-Regulated G-Protein-Coupled Receptor 1 protein
Nrg-1 protein
Sphingosine 1-Phosphate Receptor Edg-8 protein
S1p Receptor Edg-8 protein
S1pr5 protein
Edg8 protein
Nrg1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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