产品详情

  • 产品名称：Gastrin Positive Control peptide (STJ504214)

  • 产品型号：STJ504214-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Gastrin Positive Control peptide (STJ504214)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Gastrin Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: GAST
Gene ID: 2520
Uniprot ID: GAST_HUMAN
Post Translational Modifications Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
Peptide Name Gastrin Cleaved Into - Gastrin-71
Gastrin Component I - Gastrin-52
G52 - Big Gastrin
Gastrin Component Ii
Gastrin-34
G34 - Gastrin
Gastrin Component Iii
Gastrin-17
G17 - Gastrin-14
G14 - Gastrin-6
G6
Database Links Reactome: R-HSA-416476
Reactome: R-HSA-881907
Cellular Localisation Secreted
Alternative Peptide Names Gastrin Cleaved Into - Gastrin-71 protein
Gastrin Component I - Gastrin-52 protein
G52 - Big Gastrin protein
Gastrin Component Ii protein
Gastrin-34 protein
G34 - Gastrin protein
Gastrin Component Iii protein
Gastrin-17 protein
G17 - Gastrin-14 protein
G14 - Gastrin-6 protein
G6 protein
GAST protein
GAS protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图