产品详情
简单介绍:
Anti-ACSL1 antibody (46-145) (STJ118692)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF/IP |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ACSL1 (46-145) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 IP 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ACSL1 |
Gene ID: | 2180 |
Uniprot ID: | ACSL1_HUMAN |
Immunogen Region: | 46-145 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 46-145 of human ACSL1 (NP_001986.2). |
Immunogen Sequence: | TRPKPLKPPCDLSMQSVEVA GSGGARRSALLDSDEPLVYF YDDVTTLYEGFQRGIQVSNN GPCLGSRKPDQPYEWLSYKQ VAELSECIGSALIQKGFKTA |
Tissue Specificity | Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas. |
Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs). |
Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 1 Acyl-Coa Synthetase 1 Acs1 Arachidonate--Coa Ligase Long-Chain Acyl-Coa Synthetase 1 Lacs 1 Long-Chain Acyl-Coa Synthetase 2 Lacs 2 Long-Chain Fatty Acid-Coa Ligase 2 Palmitoyl-Coa Ligase 1 Palmitoyl-Coa Ligase 2 Phytanate--Coa Ligase |
Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-2046105 Reactome: R-HSA-2046106 Reactome: R-HSA-75876 |
Cellular Localisation | Mitochondrion Outer Membrane Single-Pass Type Iii Membrane Protein Peroxisome Membrane Microsome Membrane Endoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Long-Chain-Fatty-Acid--Coa Ligase 1 antibody Anti-Acyl-Coa Synthetase 1 antibody Anti-Acs1 antibody Anti-Arachidonate--Coa Ligase antibody Anti-Long-Chain Acyl-Coa Synthetase 1 antibody Anti-Lacs 1 antibody Anti-Long-Chain Acyl-Coa Synthetase 2 antibody Anti-Lacs 2 antibody Anti-Long-Chain Fatty Acid-Coa Ligase 2 antibody Anti-Palmitoyl-Coa Ligase 1 antibody Anti-Palmitoyl-Coa Ligase 2 antibody Anti-Phytanate--Coa Ligase antibody Anti-ACSL1 antibody Anti-FACL1 antibody Anti-FACL2 antibody Anti-LACS antibody Anti-LACS1 antibody Anti-LACS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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